The following adverse events have been associated with lisinopril use:
- Head and neck angioedema, including fatal events
- Intestinal angioedema
- Impaired renal function
- Acute kidney failure
- Hypotension (low blood pressure)
- Hyperkalemia (elevated blood potassium)
- Liver failure
- Pancreatitis
- Birth defects and fetal death when taken by pregnant wome
Angioedema Can Be Fatal
Angioedema is one of the most dangerous reactions to lisinopril. Most patients who experience angioedema have a reaction shortly after they start taking the drug, but in some it takes months or years of taking lisinopril before a dangerous reaction occurs. Doctors and patients can easily overlook the connection between angioedema symptoms and lisinopril use.
Angioedema is swelling below the surface of the skin. It can occur around the eyes, mouth, throat, and intestines. When swelling is in the throat or tongue, it can quickly become fatal because the airway can be blocked. Those who survive may have permanent brain injuries and severe impairment due to lack of oxygen to the brain.