Investigating Link Between Autoimmune Diseases And Wounds That Don't Heal

So Shanmugam and her colleagues conducted a chart review of people who sought care at a high-volume wound clinic at Georgetown University Hospital to determine the prevalence of autoimmune diseases. The study included patients with open wounds - usually leg ulcers who were treated during a three-month period in 2009. Of the 340 patients, 49 percent had diabetes, which she says is a typical rate.

"But what was surprising is that 23 percent had underlying autoimmune diseases, and the connection between these relatively rare disorders and wounds that don't heal is under-recognized," she says.

Of the 78 patients in the cohort who had autoimmune disease, most had rheumatoid arthritis, lupus or livedoid vasculopathy, a type of vascular disease.