To further understand this altered brain activation, Husain conducted a new fMRI study to see if there were any differences among tinnitus patients. Because some patients adjust to the ringing in the ears while others do not, the severity of the condition can vary greatly. Husain's team measured the severity of tinnitus, or tinnitus distress, with a series of surveys and questionnaires assessing hearing, attention, emotion and sleep.
Patients with lower tinnitus distress used an altered pathway to process emotional information. The path did not rely on the amygdala, commonly believed to play an important role in emotion processing in the brain. Instead, patients who had adapted to their tinnitus symptoms used more of the brain's frontal lobe, a region critical for attention, planning and impulse control. The researchers suggested that the greater activation of the frontal lobe might be helping to control emotional responses and reduce tinnitus distress.